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) and included into these prognostic methods, but none of such attempts succeeded in getting to be standard of care.ninety four–ninety six In fact, the Global Workshop on CLL (iwCLL) tips only suggest analyzing the IGHV status and presence/absence of TP53 aberrations in plan observe.
102 On the other hand, many groups are advocating for that incorporation of novel markers, for instance a intricate karyotype55 or epigenetic subsets, 27,28 into medical practice. All these novel prognostic and/or predictive designs will must be validated in cohorts of clients treated with specific brokers.
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